I started gaming on Linux at the beginning of 2019, that was afaik half a year after Proton was released, and I still remember how rough around the edges it was. Back then it still felt somewhat like a coin flip (the odds in reality were obviously a good deal better) if a game ran. Seeing how much they improved it over the last 5 years is really quite something.
I don’t think OSTree systems can quite reach the flexibility of NixOS. For instance with NixOS (with direnv and nix-shells) you can essentially swap out your running system based on the different directories you enter and I think that’s still just scraping the top of the iceberg. From my experience with OSTree (which is admittedly somewhat limited) I don’t think you can reach that level of flexibility.
It’s still really cool, I don’t mean to shit on that, I’m just saying NixOS and OSTree have different pros and cons and use cases.